Current cyber threats analysis and detection techniques, which are based on intrusion prevention and detection, and anti-virus and spam filters, often offer unsatisfactory security properties and are not very useful for securing Weapon Systems. They cannot detect new attacks, have high false negative rates and often identify attacks only after they have happened. Ensuring confidentiality, integrity, availability, non-repudiation, and authentication of Weapon Systems is essential for establishing and maintaining trusted platforms, which may operate in networked on non-networked environments. The solution for system assurance in Weapon Systems IT assets must also support the mission of the target system without adding burdensome overhead to mission-critical devices. To address this, IAI and its collaborator, Lockheed Martin, have been awarded a follow-on contract entitled, “SecureVisor: Efficiently Protect Weapon Systems Against Cyber Threats.” A lightweight whitelist-based cyber threat detection and prevention framework for Weapon Systems, called SecureVisor, will be developed. SecureVisor is composed of three major components including a whitelisting tool to identify allowed safe programs, a security enhanced hypervisor, and a Trusted Platform Module (TPM) to provide the root of trust. In all, the proposed SecureVisor is a combined hardware-software security solution to detect and prevent cyber threats to Weapon Systems. This solution will not only provide a high level of security, but will also minimize impact on the platform in terms of power, processing cycles and operation performance. It could also be used eventually for the security of commercial information and infrastructure systems.