NASA’s Space Communications and Navigation (SCaN) program is integrating three agency networks - Space Network (SN), Deep Space Network (DSN), and Near Earth Network (NEN) - to provide comprehensive, robust and cost effective space communications services. An integrated network management function, security management mechanisms and reliable autonomous satellite operations must be developed for integrated space SCaN networks. In addition, several issues related to Bundle Protocol must be investigated to enhance performance of bundle delivery in delay-tolerant networks (DTN). To address this, IAI and its collaborator, General Dynamics, have been awarded a follow-on contract entitled, “Security-Enhanced Autonomous Network Management for Space Networking.” SEANM’s key innovation is an integrated cross-layer information sharing architecture to expedite information exchange between different network layers and for necessary inter-layer interactions. A preliminary prototype has been developed and tested. Studies have been conducted on the necessary information to be shared, information sharing mechanisms and how to integrate them with the cross-layer information sharing architecture. A set of reconfigurable parameters has been identified in each layer and a robust security scheme has been designed to fight against dynamic network topology and disrupted infrastructure service. Future work will focus on autonomous bundle-based store-and-forward DTN networking. An intelligent DTN routing scheme will be designed while considering QoS and underlying resource metrics. Bundle aggregation and fragmentation schemes will enhance the end-to-end bundle delivery in the DTN environment. A DTN network management tool will enable autonomy in space networking, and provide better display of network problem and performance evaluation. SEANM also has applications in undersea networking, tactical military networks, wireless networks, vehicle networks and satellite communications.